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Revolutionizing a Way to Treat Breast Cancer: Drs. Keeney and Greco Perform First IntraOp Radiation Therapy Procedure

July 23, 2018

Drs. Keeney and Greco are performing their first Intraoperative Radiation Therapy on July 23, 2018. Our breast surgeons are the only surgeons in the area providing this treatment option. The next closest hospital offering this procedure is in New York City.
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Drs. Keeney and Greco are performing their first Intraoperative Radiation Therapy on July 23, 2018. Our breast surgeons are the only surgeons in the area providing this treatment option. The next closest hospital offering this procedure is in New York City.

What is Intraoperative Radiation Therapy (IORT)? The use of electrons in IORT enables both surgical and radiation oncologists to deliver a precise and targeted dose of controlled radiation during surgery to locally-advanced cancers. So instead of numerous radiation treatments that are localized—this a one time treatment that is targeted. For patients and their families, it means markedly shorter treatment and recovery times with improved cosmesis, greater comfort and quality of life.

Electron based IORT is the ONLY single-treatment modality affirmed by ASTRO APBI Consensus. The American Society of Radiation Oncology (ASTRO) issued an updated Consensus Statement on Accelerated Partial Breast Irradiation (APBI) in the journal Practical Radiation Oncology confirming the use of electron-beam IORT as an effective modality for the treatment of suitable patients with invasive breast cancer. Furthermore, the ASTRO Consensus removes experimental status and recognizes the single fraction electron-beam IORT modality, validating Mobetron and distinguishing it from all other IORT treatment options available in the fight against cancer.

Are You a Candidate for IORT? So is electron IORT an appropriate treatment for you and your family? Only your doctor knows for sure, but you owe it to yourself and your family to learn as much as you can about the successful outcomes that IORT can provide. Learn as much as you can. Do your research. Ask your doctor. To be eligible for IROT, your doctor will determine whether you are an appropriate candidate. IORT is most successful for early-stage patients with the following cancer incidents:

  • Breast
  • Pancreatic
  • Colorectal
  • Gynecological
  • Head and Neck
  • Sarcomas

Patient Benefits

  • More targeting radiation
  • Shorter treatment time
  • Shorter recovery time
  • Fewer side effects
  • Greater comfort
  • Lower risk of infection
  • Fewer recurring incidents
  • Better cosmetic outcomes
  • Greater rates of survivability
  • Improved quality of life

To learn more about IORT specifically with breast cancer treatment, visit Upstate Cancer Center's Website and listen to surgeon Lisa Lai, MD and radiation oncologist Anna Shapiro, MD explain the benefits of IORT on HealthLink On Air's Podcast.

Geneticist Mary-Claire King who discovered key gene linked to breast cancer to speak Oct. 28, 29

October 18, 2016

Mary Claire-King, PhD, the geneticist who discovered the BRCA1 gene that has been linked to increased breast cancer risk, will be the featured speaker at Upstate Medical University’s rst Presidential Symposium Oct. 28 and 29.
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The event will be held at the CNY Biotech Accelerator, 841 E. Fayette St., Syracuse. The event is free and open to the public with free on-site parking available.

The two-day symposium will explore genetics and precision medicine and feature two presentations by King as well as discussions with other experts.

King, professor of medicine and genome sciences at the University of Washington, is one of the leading scientists of the day.

Upstate President Danielle Laraque-Arena, MD, FAAP, said King was not only an incredible scientist but also a human rights activist. “Her visit will exemplify not only the highest level of science, but the application of science to do good,” Laraque-Arena said.

In 1990, King demonstrated that a single gene on chromosome 17q21 (which she named BRCA1) was responsible for breast and ovarian cancer in many families. Her discovery of BRCA1 revolutionized the study of numerous other common inherited diseases. The approach that King developed to identify BRCA1 has since proven valuable in the study of many other genetic diseases and conditions.

Her discovery has made it possible to screen for ovarian and breast cancers.

In addition to her genetic research on cancer, she has examined genetics of schizophrenia, genetic disorders in children and human evolution. She pioneered the use of DNA sequencing for human rights investigations. Her current research employs the use of experimental and bioinformatics genomics tools to study complex genetic diseases in humans.

In 1984 she and her laboratory worked on the Abuelas de Plaza de Mayo (Grandmothers of Plaza de Mayo) in Argentina, using genetics to identify 59 of the missing children whose mothers disappeared under the Argentine military dictatorship.

She has been honored with some of science’s biggest prizes. This past May, President Barak Obama presented King with the National Medal of Science. In presenting the medal, Obama said, Every single American should be grateful for Mary-Claire King’s path.

Earlier this year, the National Foundation for Cancer Research presented King with the Szent-Gyorgi Prize for Progress in Cancer Research.

Two years earlier she won the Albert and Mary Lasker Foundation Award, often known as America’s Nobel for her pioneering work on gene research.

Symposium schedule for Oct 28

  • 1 p.m. Keynote address by Mary-Claire King
  • 2 to 3 p.m. Presentations:
  • - “Basic science foundations of personalized medicine,” Steven Glatt, PhD, Upstate Medical University;
  • - “How science translates to medical applications,” Bernard Poiesz, MD, Upstate Medical University;
  • - “Public health implications of personalized medicine,” Erasmus Schneider, PhD, Wadsworth Center, New York State Department of Health.
  • - 3 to 4 p.m. Open discussion with moderator Rinki Argarwal, MD, Upstate Medical University.

Symposium schedule for Oct. 29

  • - 8:30 to 9 a.m. Continental Breakfast
  • - 9 to 9:30 a.m. Keynote Address: “Scientists as Citizens of the World,” Mary Claire King, PhD, University of Wisconsin.
  • - 9:30 to 10:30 a.m. Open discussion with panelists Mark Polhemus, MD, and Anna Stewart-Ibarra, PhD, MPH, both represent Upstate’s Center for Global Health and Translational Science.

For more information on the Presidential Symposium, contact the Of ce of the President at 464-4513.

Geneticist Mary-Claire King, PhD, with President Barack Obama during ceremony at the White House May 19, where she was awarded the National Medal of Science in recognition of her research into the genetics of human disease. King, a professor of genome sciences and medicine at the University of Washington, is the keynote speaker at Upstate Medical University’s rst Presidential Symposium, to be held Oct. 28 and 29.